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tBid induces alterations of mitochondrial fatty acid oxidation flux by malonyl-CoA-independent inhibition of carnitine palmitoyltransferase-1
There is some indirect evidence to suggest that excess lysine in the diet may increase endogenous L-carnitine synthesis
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These include the lipid-lowering drug Repatha, which emerged as Amgens best-selling product at $876 million worldwidea 34% year-on-year growth
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