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This combination is particularly interesting for aging-related tissue deterioration, where both mitochondrial dysfunction and impaired repair signaling contribute to declining tissue health
DISCLAIMER: STATEMENTS CONTAINED HEREIN HAVE NOT BEEN EVALUATED BY THE FDA
GHK-CU FOR HAIR RESEARCH
Cagrilintide, the second generation (2020s) Novo Nordisk took the Pramlintide concept and applied the same half-life extension strategy that they used with Semaglutide: Kept the proline substitutions (anti-amyloid) Added a C20 fatty diacid via a -Glu linker to a lysine residue, albumin binding Additionally stabilized the N- and C-terminal positions Result: Cagrilintide with a half-life of 6.6 days (vs 50 minutes for Pramlintide)
