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Its the next generation of GLP-1s, she explains, noting that unlike todays medications, Retatrutide targets three hormone pathways: GLP-1, GIP and glucagon

Technical challenges are still high with the efforts to achieve acceptable bioavailability of dual peptide combinations when administered orally, but if achieved, it could greatly increase the patient population that can be addressed by oral therapy, since the psychological barrier that exists with the use of injectable therapy are being responsible for eliminating a large number of patients who are eligible to use oral therapy

References Sun X, Deng Y, Fu X, Wang S, Duan R, Zhang Y