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Gke R, Fehmann HC, Linn T et al (1993) Exendin-4 is a high potency agonist and truncated exendin-(939)-amide an antagonist at the glucagon-like peptide 1-(736)-amide receptor of insulin-secreting beta-cells
Hypoglycemic events in this study do not appear to have been caused by AGIs because the frequencies are similar to or lower than that reported in studies on glargine or detemir (36-38)
Some women report improved mood and mental clarity on GLP-1 medications, possibly related to better blood sugar control and increased confidence from weight loss
These in vitro studies establish the compound's receptor pharmacology independent of pharmacokinetic variables
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