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These findings support the safety and potential disease-modifying effects of FUS-mediated BBB opening in early-stage AD, although larger trials are warranted to establish clinical efficacy (Rezai et al., 2024)
Multiple studies have confirmed that Cys191 in human GSDMD (Cys192 in mice) is the key site for its functional palmitoylation
Restricting calories with intermittent fasting are having positive effects on individuals with epilepsy
ROS can be regulated by glutathione peroxidases (GPxs), which are the key enzymes that maintain ROS homeostasis in vivo through the reduction of ROS [10]
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