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The effectiveness of glutathione in this capacity highlights its importance in promoting overall health and preventing diseases related to toxin buildup
Pyridoxine (B) in high doses is known to interact with certain drugs: it can reduce the therapeutic efficacy of levodopa by increasing peripheral conversion of levodopa to dopamine (vitamin B speeds up decarboxylation)
Overall, side effects are rare when used properly
These diurnal rhythm changes are also evident in at the level of cellular and organ metabolism ( Drug abuse related changes in metabolism would also have negative effects on various body systems due to increased cell damage, increased excitotoxicity, reduced energy production, and lowered antioxidant potential in cells
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