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Restored presynaptic synaptophysin and cholinergic inputs contribute to the protective effects of physical running on spatial memory in aged mice
"[Expecting a patient with chronic obesity to lose weight through willpower] is akin to having a patient with diabetes and thinking that they can concentrate really hard to bring their blood sugars down," Jastreboff continued
In clinical trials for Ozempic, participants lost an average of 13.5 pounds over 26 weeks when used in combination with moderate diet and exercise
In part, this risk relates back to one of the main benefits of GLP-1s: rapid weight loss
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