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Additionally, the cost and accessibility of Semaglutide, especially given its current use for diabetes and obesity, may pose barriers to its widespread adoption for IBS treatment
Furthermore, GLP-1 RAs exhibit anti-inflammatory effects, lowering circulating levels of pro-inflammatory cytokines such as tumor necrosis factor-alpha (TNF-), interleukin-1 beta (IL-1), and IL-6, while promoting anti-inflammatory mediator production [26]
Once-Weekly Semaglutide in Persons with Obesity and Knee Osteoarthritis (STEP PLUS)
This is concerning for mental health risks, since some doctors are prescribing semaglutide medications or other Ozempic alternatives to patients with bipolar disorder to combat the weight gain associated with antidepressants
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