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Here is some more commentary from alzforum on the liraglutide trial: According to the published trial protocol, clinical secondary outcome measures included change on the ADAS-Cog-Exec z scorewhich contains the ADAS-Cog and the executive function portion of the neuropsychological test batteryas well as the Clinical Dementia Rating Scale Sum of Boxes and the AD Cooperative StudyActivities of Daily Living (Femminella et al., 2019)

The current Wegovy prescribing information warns that combining semaglutide with these medicines increases the risk of hypoglycemia

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