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Impact of pharmacist intervention to improve medication access for patients with diabetes
While passive accumulation via the enhanced permeability and retention effect can increase tumor drug levels modestly, active targeting through ligand-receptor interactions enables selective binding to cancer cell membranes, triggers receptor-mediated endocytosis and delivers intact nanoparticles directly into the cytoplasm, thereby bypassing P-glycoprotein efflux pumps stationed at the plasma membrane [120, 121]
A versatile polymer that helps to thicken up products and can also act as an emulsifier, enabling gel-cream-like textures
Ethics declarations Competing interests Through M.H.H.K., the VU University Medical Center has received research grants from AstraZeneca, Boehringer Ingelheim, Novo Nordisk and Sanofi
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