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Needle phobia affects an estimated 20-30% of the adult population, and the logistics of cold-chain storage, injection site management, and weekly self-administration limit the reach of these therapies to a fraction of the eligible patient population
At the same time, gastrointestinal tolerability and other safety observations remain important when interpreting the overall research profile
The Research Gaps: What We Don't Know Studies show GLP-1s are equally effective for weight loss in post-menopausal and pre-menopausal women, with some limited evidence of enhanced benefits when combined with hormone therapy
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