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The study included subjects with mild, moderate, and life-threatening kidney impairment, and end-stage kidney disease requiring dialysis, andindividuals with regular kidney function
With regard to Trp metabolites, serum levels of Trp ( p = 0.00101), Kyn ( p = 0.00568), and 5-HT ( p = 0.0131), but not KYNA ( p = 0.6145), were significantly altered
A 2021 research review found in multiple studies that taking 2.4 mg of Wegovy once per week led to reductions in weight and was more effective than a placebo
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