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Theres a reason they are all gastrointestinal: GLP-1s impact gut hormones and slow down gastric emptying (or how quickly you digest food), which can trigger the side effects

Germany Focuses on Private Sector Treatment Access Demand for obesity GLP-1 treatment in Germany is projected to grow at a CAGR of 19.6%, constrained by statutory health insurance exclusions for anti-obesity medications that limit public reimbursement

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This is the ground floor in the advance of GLP-1-based weight loss drugs