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One such mechanism occurs within immune cells, which require sufficient glutamine as a substrate for leukocyte function, cell proliferation, tissue repair, and intracellular pathogen recognition pathways

Sometimes, these are significant changes, like during pregnancy or after a weight loss surgery

Its Phase 3 weight-loss figures (in the low-to-mid 20% range) and its late-2025 FDA filing belong to the combination product, not to standalone cagrilintide, which remains at the Phase 2 stage with a peer-reviewed monotherapy result of about 10.8% at 26 weeks