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The GAD2 gene is located on chromosome 10p12.1 and is composed of 16 exons that generate two alternatively spliced mRNAs, both of which encode the same 585 amino acid protein (GAD 65 )
Cloning and expression of a plasma membrane cystine/glutamate exchange transporter composed of two distinct proteins
According to the NHS, the usual pattern depends on the cause: Non-dietary cause (for example an absorption problem): an injection of hydroxocobalamin every two to three months, usually for life
Some practitioners advocate weight-based dosing (e.g., 2.5-5 g/kg daily), while others use fixed doses (250-500 g daily) regardless of body size
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