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Probe sensitivity to cortical versus intracellular cytoskeletal network stiffness

Caspase-3 activation is an early event and initiates apoptotic damage in a human leukemia cell line

ACSL4 acylates AA, LPCAT3 catalyzes the acylated AA into membrane PLs, and then lipoxygenases (LOXs) catalyze PUFA PLs, producing native lipid peroxidation (41) (Figure 1)