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GLP-1 is studied in the context of insulin secretion, glucose metabolism, and appetite signaling, while GLP-2 is investigated for its role in intestinal epithelial biology
The biology of obesity includes genetic predisposition, neurohormonal signaling disruptions (particularly in the hypothalamus) and alterations in appetite-regulating hormones
Retatrutide might result in more frequent or severe gastrointestinal side effects, including nausea and diarrhea, than tirzepatide
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