DESTINY-Lung01, a phase II trial evaluating the efficacy of T-DXd in pre-treated NSCLC harboring HER2 molecular alterations includes two cohorts of patients: The HER2 -mutant cohort included 91 patients, showing an ORR of 55%, a median DoR of 9.3 months (95% CI, 5.7 to 14.7) and medians PFS and OS of 8.2 (95% CI, 6.0 to 11.9) and 17.8 months (95% CI, 13.8 to 22.1), respectively [4,33,34]
Real-world results vary hugely with diet, training, sleep, and starting weight
Always inform your GP about all treatments you are receiving
If youre deciding between formats based on clearance or detection, injections may remain active slightly longerbut both forms clear within 2448 hours , depending on dosing