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The escalating global prevalence of MASLD is concerning, as the disease can progress silently to liver fibrosis, cirrhosis, and hepatocellular carcinoma (HCC)
Both reactions can be catalysed by protein disulphide isomerase (PDI) and possibly other oxidoreductases that share common domains with PDI (for a recent review, see Ellgaard & Ruddock, 2005)
PLGA is insoluble in aqueous media, but it can dissolve in organic solvents, such as acetone and dimethylformamide (DMF) 109
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