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NNMT is an enzyme that grabs nicotinamide and methylates it, turning it into a waste product called 1-MNA that gets cleared from the body
[13] Chloramphenicol has been shown to blunt reticulocyte response to cyanocobalamin, while ethanol, colchicine, and nitrous oxide interfere with cobalamin metabolism or utilization, each warranting clinician awareness when evaluating suboptimal treatment outcomes
In the 2007 Pyo study, AHKCu made these cells divide more and showed fewer signs of programmed cell death
As of writing, studies in laboratory animals have not identified significant safety concerns [3, 4]
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