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2: moderate
Research investigations involving BPC-157 have examined its effects on nitric oxide (NO) synthase expression and NO-mediated signaling in vascular and mucosal tissue cell models, FAK-paxillin pathway involvement in cell migration assays, and VEGFR2 receptor activation dynamics in in vitro angiogenesis models
While the peptide was generally well-tolerated, it failed to perform significantly better than a matching placebo
However, significant safety concerns and lack of regulatory approval limit their clinical utility
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