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Very few patients can get the full 4 daily doses in timing-wise, but honestly most would not tolerate that much CSM anyway, and 2 seems to be about the average
Response of hepatic biochemical parameters and neurotoxicity to carbamazepine and ibuprofen in Oreochromis mossambicus
A 2001 editorial in the European Journal of Anaesthesiology described DSIP as "incredibly safe," noting that no dose had ever killed an animal subject in research, and the only human side effects observed were transient headache, nausea, and vertigo
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