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At the same time, metformin can indirectly affect tumorigenesis by affecting insulin levels and inducing energy stress (Pernicova and Korbonits, 2014)

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Although the discussion of these guidelines is beyond the scope of this article, it is worth mentioning that we have included the rate of GI symptoms associated GLP-1RAs in our meta-analysis, because the ASA considered the presence of severe GI symptoms preoperatively, a surrogate for increased RGC

DOI: 10.1073/pnas.2410653121 [Google Scholar] Wijesinghe SN, Ditchfield C, Flynn S, Agrawal J, Davis ET, Dajas-Bailador F, et al