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21 Remarkably, even in HF-free patients with morbid obesity, cardiac abnormalities can be seen that are consistent with left ventricular (LV) remodelling and dysfunction, including greater LV mass, LV diastolic dysfunction and elevated LV filling pressure

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BPC-157 is a linear chain of fifteen residues: Gly-Glu-Pro-Pro-Pro-Gly-Lys-Pro-Ala-Asp-Asp-Ala-Gly-Leu-Val Four structural features explain much of its experimental behaviour: near the N-terminus impose conformational rigidity and resist enzymatic cleavage, which accounts for its unusual stability relative to most short peptides