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The composition of item1, wherein the at least one stimulant chemically attached to a polar hydrophilic ligand, the salt thereof, the derivative thereof, or the combination thereof is provided to the human or animal in an amount sufficient to provide therapeutic effectiveness when compared to the at least one stimulant alone, but provide no or substantially lessened rebound effect
It also provides new insights into developing convenient, efficient, and safe local delivery systems, which may lead to clinical applications
Dietary intake was assessed using the FFQ, which estimates total energy and macronutrient intake over a 1- to 2-month period
It was founded in 1980 by businessman Mark Hughes, who was only 24 at the time
