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It is a substrate: cells need it to run the electron transport chain, generate ATP, and activate a class of repair enzymes called sirtuins and PARPs
it only changes how much liquid you have to inject to get your dose
180-182 For example, in patients with atrial fibrillation, high homocysteine (often from B12 deficiency) increases the risk of stroke four-fold
As of mid-2026, neither compound is approved by the FDA or the EMA for any indication , so no established or approved human dose exists for either, and anything sold under those names outside a monitored trial is a research-use-only chemical of unverified identity
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