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Important nteractions one should check out for: Corticosteroids additive hyperglycemic Thiazide diuretics additive glucose elevation Non-selective beta-blockers (e.g., propranolol) can mask hypoglycemia symptoms in insulin/sulfonylurea users CYP1A2 modulators (e.g., smoking cessation during admission) can raise olanzapine levels unexpectedly QT-prolonging co-prescriptions (fluoroquinolones, macrolides, ondansetron) additive QTc risk Anticholinergic burden can worsen diabetic gastroparesis 3.Interventions Baseline and periodic fasting glucose, lipid panel, weight/BMI Track HbA1c trend from olanzapine initiation Discuss risk-benefit of lower metabolic-risk alternatives (e.g., aripiprazole) where clinically appropriate Don't dismiss deteriorating glucose control as "just illness stress" screen actively This is the kind of case that reminds us why the pharmacist's seat at the ward round table matters catching interactions that aren't always obvious on a first glimpse of a prescription
3 Disruption of carnitine availability leads not only to impaired fatty acid metabolism, but also to clinical manifestations
Tsai 2004b)
Cold water can slow gastric emptying further, so room temperature or warm water is preferred
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