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Semaglutide, a glucagon-like peptide-1 (GLP-1) receptor agonist, is gaining attention not only for its blood glucose-lowering effects but also for its ability to improve liver function and reduce liver fat accumulation, which is particularly beneficial for MASLD patients who often have coexisting T2DM
A 30-second check with a thermometer catches drift before it becomes a problem
No adverse developmental effects were observed when sitagliptin was administered to pregnant rats and rabbits during organogenesis at oral doses up to 30-times and 20-times, respectively, the 100 mg clinical dose, based on AUC
For semaglutide, while the core patent (protecting the molecule itself) expires in 2026, Novo Nordisk has likely filed secondary patents on aspects like formulations, dosage regimens, or delivery mechanismspotentially extending protection into the 2030s
