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The story is the same for someone doing a diet-only weight loss, someone recovering from bariatric surgery, and someone on semaglutide or tirzepatide
Preclinical studies demonstrate that sustained GLP-1 receptor activation alters mesolimbic dopamine signaling over a period of time, and emerging studies suggest that behavioral and craving-related effects require continued exposure (26, 27)
Research questions that span multiple complementary biological pathways benefit from the four-pathway framework
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