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It is prescribed off-label based on clinician judgment and emerging research
it is available for research purposes, and quality varies widely by supplier
We found that PD-1 + non-exhausted-like T cells (PD-1 + Lag-3 ) displayed higher levels of GSH than exhausted-like (PD-1 + Lag-3 + ) and other control cell subsets (Supplemental Figure 1O), while stem-like progenitors (Ly108 + CD69 + ) displayed the highest levels of GSH among all cell subsets in transferred infiltrating CD8 + T cells (Supplemental Figure 1P)
Conversely, if genetic variants suggest faster metabolism, an optimized higher dose may deliver superior results
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