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Eli Lilly's tirzepatide (Mounjaro/Zepbound), a dual GIP/GLP-1 receptor agonist, has demonstrated superior weight loss outcomes (approximately 22.5% mean weight reduction in SURMOUNT-1 versus 14.9% for semaglutide), and its accelerating market penetration in the United States is beginning to exert competitive pressure on semaglutide's market share in the weight management segment

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