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During IF, several neuroprotective proteins, including protein chaperones such as heat shock protein 70 (HSP70), glucose-regulated protein 78 (GRP-78), neurotrophic factors such as brain-derived neurotrophic factor (BDNF) and fibroblast growth factor 2 (FGF2), and antioxidant enzymes such as superoxide dismutase and heme oxygenase-1, are up-regulated in animal models of stroke (Arumugam et al
The body knows how to process them, which often results in fewer side effects compared to synthetic drugs
If using during the day, follow with sunscreen for best results
If you have a temporary skin issue on one thigh (a rash, scrape, or bruise from exercise), simply switch to the other thigh or use the abdomen as an alternative site
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