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A common community-reported on-cycle profile: Phase 2 trial titration moved faster: 2 mg/week for weeks 1-4, 4 mg/week for weeks 5-8, 8 mg/week for weeks 9-12, then 12 mg/week from week 13 onward
One example escalation schedule observed in Phase 2 obesity trials proceeded broadly as follows: Weeks 14: 2 mg once weekly (initiation phase) Weeks 58: 4 mg once weekly Weeks 912: 8 mg once weekly Weeks 13 onwards: Up to 12 mg once weekly (the maximum dose explored in Phase 2 trials) This is an illustrative example only
Overexpression of erythrocyte glutathione S-transferase in uremia and dialysis [PMID: 10508125] Laboratory literature summary: Overexpression of erythrocyte glutathione S-transferase in uremia and dialysis
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