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But repeated sessions especially at high doses can increase cumulative risk
The most often and potent ones attracted are the insulin receptor substrates 1/2 (IRS1/2)although there are 6 found to date- (not to forget that Shc proteins, p60dok, Cbl, APS, and Gab-1 are also recruited to activated IRs)
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To eliminate freeze-thaw stress, stock solutions should be aliquoted into single-use experimental volumes immediately following reconstitution
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