Oxidation, or oxidative stress and the subsequent reactive oxygen species (ROS) and reactive nitrogen species (RNS) increases tremendously when we become injured, when we have an infection (such as a flu virus, gingivitis, Epstein Barr virus, Herpes virus, etc.) and/or inflammation, such as from leaky gut and food sensitivities
Skipping doses or irregular usage reduces results
23, 24, 25 In three independent case/control cohorts, children with autism were shown to exhibit abnormal plasma levels of metabolites in the pathway of glutathione redox metabolism
The alpha class genes, located in a cluster mapped to chromosome 6, are the most abundantly expressed glutathione S-transferases in liver (hepatocytes) and kidney (proximal tubules)