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JAMA Internal Medicine
Vitamin B12 plays a critical role in energy metabolism, protein synthesis, and oxygen transport
No thyroid C-cell tumors were observed in human trial participants, though this risk carries a theoretical basis from rodent studies and is listed as a precaution, as it is with all GLP-1 class compounds
[9] Because NNMT acts inside cells, an effective inhibitor has to get into cells throughout the body which is exactly why absorption and route matter, and why the membrane-permeability finding was highlighted in the first place
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