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Fruits high in Vitamin C, such as oranges and strawberries
A key driver of neuronal injury is oxidative stress, which arises when the generation of reactive oxygen species (ROS) overwhelms the brains antioxidant defenses, one such defense being glutathione (GSH) (Dringen and Arend, 2025)
This moiety is subsequently transferred to a conserved lysine in the E2 component of the -ketoacid dehydrogenase complexes by lipoyl transferase 1 (see Figure 4)
These are distinct but complementary pathways that together create a more comprehensive metabolic profile than either compound alone
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