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In specifically, the Mn-SOD ratio (levels in normal and malignant tissue) is demonstrated as an independent predictive indicator in patients of gastric cancer, and it appears to be therapeutically relevant for the survival of patients, the higher the ratio, the poorer overall survival (163)
The NWLSS Glutathione Assay is a modification of the method first described by Tietze
The primary endpoint, median OS was 6.5 months for patients with sorafenib and 4.2 months for patients with placebo (Llovet et al., 2008)
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