Common side effects Most side effects involve the stomach, tend to be mild to moderate, and usually ease as your body adjusts: Nausea Diarrhea Vomiting Stomach pain, bloating, and constipation Indigestion, heartburn (GERD), and burping Headache, dizziness, and tiredness Reduced appetite and weight loss Low blood sugar, mainly when taken with a sulfonylurea or insulin Serious side effects Get medical help right away if you notice any of these: Who should not take semaglutide
Semaglutide also delays the emptying of the stomach, which helps reduce appetite and promote satiety
You can expect to see gradual improvement over 2-4 weeks as your body naturally eliminates the broken-down fat cells through the lymphatic system
Important safety information includes a boxed warning for risk of thyroid C-cell tumors, with contraindications in patients with personal or family history of medullary thyroid carcinoma (MTC) or Multiple Endocrine Neoplasia syndrome type 2 (MEN2)