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found that lncRNA-N1LR was neuroprotective in IS-I/R by inhibiting p53 phosphorylation on serine 15 and inactivating p53 (Wu et al., 2017)

p53 inhibition of GLS promotes glutamine's use for biosynthetic processes like nucleotide production, preventing excess -KG production in specific cellular contexts

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Alcohol activates activator protein-1 and mitogen-activated protein kinases in rat pancreatic stellate cells