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Available as consumer-facing supplements and as licensable functional food ingredients for the food and beverage industry, Pivit's patented weight management formulations are engineered to stimulate secretion of GLP-1 alone, GLP-1 and GIP together, or the full triple-hormone axis of GLP-1, GIP, and Peptide YY (PYY)
The key protease responsible for the processing of the proglucagon peptide into GLP-1 is Psck1/3, which has shown to be upregulated in -cells during hyperglycaemic, hyperlipidemic, or inflammatory conditions to promote glucose-induced glucagon suppression, a compensatory response to a metabolic insult as in type 2 diabetes (205)
With last weeks approval of Tirzepatide for obesity, the combined power of a GLP-1 with another gut hormone enhancer (GIP) has shown even more promise with losses of up to an astounding 48 pounds or 21% of body weight at 88 weeks vs
The consistent finding is reduced neuronal damage and improved functional recovery on standardized scoring scales
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