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However, obesity also appears to play an independent role in CKD risk and progression by triggering increased inflammatory signaling, oxidative stress, and gut microbiome disturbance, as well as premature cellular aging and dysfunction
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3), and the backbone of each complex also closely resembled the previously determined active structures of individual AMYRs bound to rat Amy (rAmy) 15 (Fig
found that administration of GSH and its precursor NAC reduced lipid peroxidation and oxidative tissue damage in patients with early septic shock, affirming the therapeutic viability of antioxidant co-therapy in acute care settings (Ortolani et al., 2000)
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