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When GLP-1 reaches the pancreas, it binds to the GLP-1 receptors (GLP-1R) expressed on pancreatic cells, stimulating insulin release
In patients with PCOS, endometrial GLUT4 expression is decreased, and glucose transport and utilization are impaired, leading to endometrial energy metabolism disorders, which in turn affect the establishment of endometrial tolerance
It is usually applied to the skin one or two times a day for several weeks
Because of the intended therapeutic use, it is of substantial importance that side effects, such as nausea, be minimized
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