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Access the full publication through NEJM.org for detailed methodology, adverse event data, and subgroup analyses
Applying a cold compress and avoiding rubbing the area can provide relief
Though generally safe, following the recommended dosage guidelines is crucial for avoiding potential negative side consequences
When B12 levels are equivocal, additional testing with methylmalonic acid (MMA) and homocysteine levels can provide greater diagnostic accuracy, as both are elevated in true B12 deficiency
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