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It recently has been reported to have a rate ratio of 1.6 (95% confidence interval 1.12-2.09) (43)
Previous studies have shown that Epidermal Growth Factor Receptor (EGFR), CD44v (an adhesion molecule expressed in cancer stem-like cells) and OTU deubiquitinase, ubiquitin aldehyde-binding 1 (OTUB1), control and stabilize SCL7A11 expression, facilitating Cys uptake by tumor cells (Ishimoto et al., 2011
Bibcode:2014PLoSO...9j1320D
That said, "well tolerated" is not the same as "risk-free," and responsible buyers should understand both the safety profile and the limits of the evidence
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