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Description

To overcome drug resistance and enhance its cytotoxicity, two derivatives of DOX were synthesized incorporating a sulfonamide moiety: 4-mononitrobenzenesulfonyl DOX (MNS-DOX) and 2,4-dinitrobenzenesulfonyl DOX (DNS-DOX) 94

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Human PET scans indicate that 10-30% of striatal DATs are bound by drug at therapeutic concentrations of bupropion (Stahl, 2013)

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Psychiatry 5 , e583e583 (2015)

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