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Call 999 immediately for life-threatening symptoms such as anaphylaxis, severe chest pain, or signs of sepsis
The most well-known are semaglutide (Ozempic, Wegovy) and tirzepatide (Mounjaro, Zepbound)
Even though the 3D structure of OCTN2 is still not known, the molecular determinants for substrate specificity have been revealed: one ammonium and one carboxylate groups are strictly required for transport, while the distance between them is not important (Ohashi et al., 2002
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