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In cancer, deregulation of genes involved in these pathways may lead to unwarranted activation of oncogenes or inactivation of tumor suppressor genes ( 3.1 Histone acetylation Histone acetyltransferases (HATs) catalyze the transfer of an acetyl group to the -amino group of the lysine side chains utilizing the cofactor acetyl CoA, thereby weakening the DNA and histone interactions

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10.1021/acsnano.0c01676 35 HeS.LiC.ZhangQ.DingJ.LiangX.-J.ChenX.et al (2018)