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Skin mast cells carry MRGPRX2, a receptor that fires on cationic, aromatic ("cationic amphiphilic") molecules and releases histamine redness, swelling, the classic wheal. It is confirmed for SS-31, which activates the receptor well below its injection concentration
First, most trials used the compound preparation of L-carnitine and other substances in the intervention group
The samples were analyzed by a FACS Calibur Flow Cytometer (BD Biosciences, USA)
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