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Amplifications of MET, KRAS, or other oncogenes can activate parallel or downstream signaling pathways, effectively bypassing the inhibited target and restoring oncogenic signaling
Prioritizing protein at every meal, even in small portions, is essential for preserving lean mass and maintaining long-term weight loss
Consistent receptor engagement could also sustain continuous metabolic benefits, such as appetite suppression, without weekly troughs that might reignite hunger between doses
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